MCE and partners receive $3.2 mil National Institute of Health grant

Developing and Evaluating Tests that Measure & Track Cognitive Functioning

Karen Riley - Desk

Dr. Karen Riley

Multi-site project validates existing tests that track improved thinking and problem-solving skills in people with fragile X syndrome, Down syndrome, and other intellectual disabilities.

Researchers with The Morgridge College of Education at The University of Denver are partners in a multi-site project that validates existing tests designed to measure and track changes in the cognitive functioning of people who are typically difficult to assess accurately. The research is funded through a, five-year, $3.2 million grant from the National Institutes of Health (NIH).

Principal investigators, Karen Riley Ph.D., Dean and Associate Professor, The Morgridge College of Education; Elizabeth Berry-Kravis Ph.D. M.D., Associate professor,  Rush University Medical Center, Chicago; David Hessl Ph.D., Professor, UC Davis Mind Institute; and Richard Gershon Ph.D., Associate Professor, Northwestern University School of Medicine participate in this ground breaking research.

“The importance of appropriate outcome measures is foundational for intervention research. This project provides an opportunity for The University of Denver to collaborate with national leaders in the field and to partner with researchers at The Children’s Hospital, including Dr. Nicole Tartaglia in the Child Development Center and Dr. Fran Hickey in the Anna and John J Sie Center for Children with Down syndrome. It also provides a unique research opportunity for our students and builds capacity within our community to support children and their families with neurodevelopmental disorders,” said Dean Riley.

The tests will eventually be used to ascertain the effectiveness of medications and other treatments, specifically for people with fragile X syndrome and Down syndrome and other intellectual disabilities. Fragile X syndrome and Down syndrome are among the leading causes of intellectual disabilites in the United States and around the world. Fragile X syndrome also is the leading single-gene cause of autism spectrum disorder.

Research Partners

National Institute of Health Grant
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